Manuel B. Garcia

Manuel B. Garcia serves as the Senior Director for Educational Technology and Digital Learning at FEU Institute of Technology, Manila, Philippines. Read More

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What Is an Exploratory Sequential Mixed-Methods Design?

An exploratory sequential mixed-methods design begins with qualitative inquiry and uses its findings to develop a subsequent quantitative investigation. Learn when this design is appropriate, how to connect the phases, and why qualitative exploration does not replace quantitative measurement or intervention evaluation.

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Exploratory Sequential Mixed-Methods Design Guide 322 of 1272
01 · The Question

What If You Cannot Measure a Phenomenon Adequately Until You Understand It?

You want to investigate how university teachers make decisions about using generative AI in assessment. A survey could help establish how widely particular practices occur, but you are uncertain whether existing questionnaires adequately represent those practices.

Teachers may interpret responsible AI use differently, distinguish among assessment activities in unexpected ways, or encounter institutional conditions that established instruments overlook. Developing survey items before investigating these differences could impose categories that do not reflect the phenomenon.

One possibility is to begin with qualitative interviews, use the findings to develop a questionnaire, and then evaluate and administer that questionnaire quantitatively. But what makes this arrangement an exploratory sequential mixed-methods design rather than simply a qualitative study followed by a survey?

The distinction matters because the design requires a developmental relationship between phases. Qualitative findings must meaningfully shape the quantitative investigation, and the resulting evidence must contribute to a coherent overarching research purpose.

02 · The Short Answer

Exploratory Sequential Research Builds Quantitative Inquiry From Qualitative Findings

In Brief

An exploratory sequential mixed-methods design begins with qualitative data collection and analysis, uses the qualitative findings to develop or inform a subsequent quantitative component, and integrates the contributions of both phases to address an overarching research question.

The design is particularly appropriate when researchers need to clarify constructs, develop instruments, identify relevant variables, or inform interventions before quantitative investigation. However, the initial qualitative findings do not automatically establish the validity of a resulting instrument or the effectiveness of an intervention.

03 · What You Need to Know

Understanding the Logic and Procedures of Exploratory Sequential Mixed Methods

What Makes the Design Exploratory and Sequential?

The term exploratory describes the initial purpose of investigating a phenomenon whose relevant dimensions, interpretations, or contextual characteristics require further understanding before quantitative inquiry can proceed appropriately.

The term sequential indicates that the qualitative component precedes the quantitative component and informs its development.

Both characteristics are essential. A researcher who conducts interviews in January and an unrelated survey in March has not necessarily implemented exploratory sequential mixed methods.

The defining relationship is developmental. What researchers learn during qualitative inquiry influences what they subsequently measure, investigate, or evaluate quantitatively.

Fetters, Curry, and Creswell (2013) describe this form of methods-level integration as building, in which findings from one component inform the data collection procedures of another.

The design therefore extends beyond using both forms of evidence. It establishes an explicit relationship between qualitative understanding and quantitative investigation.

What Are the Main Phases of an Exploratory Sequential Design?

An exploratory sequential study commonly involves an initial qualitative investigation, a developmental transition, a quantitative phase, and integrated interpretation.

Phase 1: Qualitative exploration

Investigate participants' experiences, meanings, practices, or contextual conditions using an appropriate qualitative methodology.

Qualitative analysis

Develop findings that identify relevant dimensions, distinctions, processes, or contextual requirements.

Integration through development

Use the qualitative findings, together with relevant theory and existing evidence, to inform quantitative instruments, variables, intervention components, or research procedures.

Phase 2: Quantitative investigation

Collect and analyze numerical evidence to evaluate the developed instrument or intervention, examine patterns, or address another defined quantitative objective.

Integrated interpretation

Explain how the qualitative findings shaped the quantitative component, what the quantitative results established, and how both phases contribute to the overarching conclusion.

The developmental transition may involve substantial methodological work. Researchers should not assume that questionnaire construction or intervention development can be completed immediately after qualitative coding.

When Should You Use Exploratory Sequential Mixed Methods?

The design is appropriate when the quantitative investigation depends on knowledge that must first be developed through qualitative inquiry.

Several research situations may justify this arrangement.

Research situation Qualitative contribution Quantitative contribution
An emerging construct is insufficiently understood. Identify relevant meanings, dimensions, and practices. Develop and evaluate measures representing the construct.
Existing instruments do not adequately fit the target population. Investigate terminology, contextual relevance, and response interpretations. Evaluate an adapted instrument for its intended use.
A new intervention requires contextual development. Explore participant needs, implementation conditions, and perceived barriers. Evaluate feasibility, implementation, or outcomes.
Relevant variables or categories are uncertain. Identify distinctions that warrant further investigation. Operationalize and examine selected constructs or relationships.
Professional practices are changing. Investigate how participants understand and enact emerging practices. Examine the distribution or associations of appropriately defined practices.

These circumstances do not automatically require a mixed-methods design. Researchers should first establish whether existing theory, empirical studies, or suitable instruments already provide an adequate basis for quantitative investigation.

How Is Exploratory Sequential Different From Explanatory Sequential?

Both designs involve connected phases, but they begin with different forms of inquiry and address different methodological needs.

Exploratory sequential: QUAL → QUAN Qualitative findings inform the development or design of subsequent quantitative investigation.
Explanatory sequential: QUAN → QUAL Quantitative findings guide subsequent qualitative inquiry intended to explain or clarify the numerical results.

The uppercase notation shown here indicates sequence only for simplicity; formal mixed-methods notation often uses capitalization to communicate priority, so researchers should define their chosen convention.

The more important distinction is the integration purpose. An explanatory sequential design commonly investigates the meaning of quantitative findings, whereas exploratory sequential research uses qualitative findings to shape what comes next.

Does the Qualitative Component Have to Be Conducted First?

Yes, in the sense that the relevant qualitative findings must be available before the quantitative procedures they are intended to inform are finalized.

Researchers can prepare administrative arrangements, ethical approvals, sampling plans, and preliminary quantitative procedures in advance. However, decisions that depend on qualitative findings should remain responsive to those findings.

For example, a researcher can plan the broad structure of a survey before conducting interviews, but should not claim that the survey dimensions emerged from qualitative inquiry if they were finalized beforehand and remained unaffected by the findings.

The sequence must represent a genuine developmental dependency rather than a retrospective description of unrelated activities.

Must the Qualitative Component Have Greater Priority?

No. Collection order and methodological priority are separate characteristics.

A qualitative phase may be primarily developmental, while the quantitative phase carries the principal research emphasis. This can occur when interviews inform a questionnaire that is subsequently used to examine a central quantitative research question.

Alternatively, the qualitative investigation may make the primary conceptual contribution, with quantitative evidence examining the distribution or applicability of selected findings.

Some studies assign comparable importance to both phases.

Researchers should justify the relative priority of the components according to the overarching research purpose rather than the order in which data are collected.

How Can Qualitative Findings Inform Questionnaire Development?

One common application is the development of a quantitative measurement instrument from qualitative findings.

Suppose a researcher wants to measure teachers' responsible use of generative AI in assessment. Interviews might reveal distinctions among disclosure practices, verification of AI-generated materials, and responsibility for assessment decisions.

These findings could inform candidate constructs and survey items. However, the researcher must interpret them alongside relevant theory, previous empirical evidence, and the intended measurement purpose.

Boateng and colleagues (2018) describe scale development as a process involving item development, scale construction, and evaluation. Their guidance helps distinguish generating candidate items from establishing evidence supporting the resulting measure.

The researcher should document how particular qualitative findings informed specific item-development decisions. A development matrix can make this relationship transparent.

The process of using qualitative findings to develop quantitative instruments requires conceptual judgment and subsequent measurement evaluation.

Does Exploratory Sequential Research Automatically Produce a Valid Instrument?

No. Qualitative inquiry can contribute to the conceptual foundation and content of an instrument, but it does not establish all the evidence needed to support the interpretation and use of its scores.

The Standards for Educational and Psychological Testing emphasize that validity concerns the evidence and theory supporting particular score interpretations for intended uses.

Depending on the instrument, researchers may need evidence concerning content, response processes, internal structure, relationships with other variables, and the consequences of testing.

Reliability, measurement precision, and appropriateness for the intended population also require consideration.

For example, items derived from interviews may appear relevant but fail to exhibit the expected measurement structure when administered quantitatively.

Researchers should report the specific evidence obtained rather than describing an instrument as validated simply because it originated from qualitative findings.

Can Exploratory Sequential Research Be Used to Develop an Intervention?

Yes. Qualitative inquiry may inform the development of an educational intervention when participant needs, contextual conditions, or implementation barriers are insufficiently understood.

For example, interviews with teachers could identify difficulties in designing assessments that incorporate generative AI responsibly.

The findings might inform a professional development intervention, including its learning activities, examples, and implementation supports.

However, intervention development should also draw on relevant theory and existing evidence. Participant preferences alone do not establish that particular intervention components will be effective.

Skivington and colleagues (2021) emphasize the importance of context, program theory, stakeholder engagement, and evaluation when developing complex interventions.

A subsequent quantitative component might examine feasibility indicators, implementation outcomes, or intervention effects, depending on the research objective and design.

The researcher should distinguish developing an intervention from demonstrating that it works.

How Should Qualitative Findings Be Translated Into Quantitative Variables?

Qualitative themes do not automatically become quantitative variables.

A theme may describe a contextual condition, an interpretive process, or a complex experience that cannot be adequately represented by a single numerical indicator.

Researchers should first determine whether the proposed variable has a defensible conceptual definition and whether it can be operationalized meaningfully.

For example, interviews may identify teachers' concerns about accountability for AI-supported assessment decisions. The researcher must decide whether accountability is best conceptualized as a belief, a reported practice, an institutional condition, or another construct.

These possibilities imply different measurement approaches.

Prematurely converting every qualitative theme into a survey scale may produce redundant or conceptually confused instruments.

How Should Participants Be Sampled Across the Two Phases?

Qualitative and quantitative phases often use different sampling strategies because they serve different inferential purposes.

The qualitative phase may use purposive sampling to investigate relevant experiences and variation in the phenomenon. The quantitative phase may require a larger or differently selected sample to support measurement evaluation, statistical comparisons, or population inference.

The same participants do not necessarily need to participate in both phases.

For example, interviews with teachers from several disciplines may inform questionnaire development, while a separate sample of teachers completes the questionnaire during quantitative evaluation.

However, the researcher should consider whether the qualitative participants adequately represent the contexts and perspectives relevant to the intended quantitative population.

The relationship between samples should be justified rather than determined by convenience alone.

How Much Qualitative Evidence Is Enough Before the Quantitative Phase?

There is no universal number of interviews or observations that establishes sufficient qualitative exploration.

Sample adequacy depends on the research question, qualitative methodology, sampling strategy, heterogeneity of the phenomenon, and depth of information required for the developmental purpose.

For example, developing an instrument for a narrowly defined professional practice within a relatively homogeneous population may require a different sampling strategy from investigating an emerging construct across multiple institutional contexts.

The researcher should determine whether the qualitative evidence is sufficiently developed to support the decisions required for the next phase.

This does not mean every possible perspective must be exhausted. Rather, the qualitative analysis should provide a defensible foundation for the intended quantitative development.

Where Does Integration Occur in Exploratory Sequential Research?

Integration commonly occurs when qualitative findings inform the quantitative component and again when the contributions of both phases are interpreted together.

The developmental transition is especially important.

For instrument development, researchers can document which qualitative findings informed candidate dimensions, items, or response formats.

For intervention development, they can explain how participant experiences and contextual findings influenced intervention content or implementation arrangements.

The subsequent quantitative findings may support, complicate, or challenge the original conceptualization.

Researchers should therefore plan the points of integration and document the reasoning connecting phases.

What If the Quantitative Findings Do Not Support the Qualitative Framework?

The quantitative phase may reveal that proposed dimensions overlap, particular items perform poorly, or expected relationships are not supported.

Such findings should not automatically be interpreted as failure.

They may indicate limitations in the proposed measurement model, differences between the qualitative and quantitative samples, or a need to reconsider how the construct was operationalized.

Researchers should distinguish measurement problems from substantive disagreements about the phenomenon.

For example, a proposed questionnaire dimension may fail to emerge as a distinct statistical factor. This does not necessarily mean that the experiences represented by the qualitative theme are unimportant.

It may mean that the items do not adequately distinguish the proposed dimension or that the conceptual structure requires refinement.

Any revisions should be supported by evidence and reported transparently.

What Are the Advantages and Limitations of Exploratory Sequential Design?

Potential Advantages

  • Quantitative procedures can be informed by participants' experiences and contextual understanding.
  • Emerging constructs can be investigated before they are operationalized.
  • Instruments and interventions may be developed with greater attention to the intended population.
  • The developmental relationship provides an explicit opportunity for integration.

Potential Limitations

  • The quantitative phase depends on sufficiently completing qualitative analysis and development.
  • Translating qualitative findings into quantitative measures may oversimplify complex phenomena.
  • Qualitative sampling may overlook relevant perspectives in the intended quantitative population.
  • Instrument or intervention evaluation may require substantial additional time and resources.
  • Researchers may overstate the validity or effectiveness of products developed from qualitative findings.

When Is Exploratory Sequential Design Not Appropriate?

The design may be unnecessary when the relevant constructs are already well established and suitable quantitative instruments exist.

It may also be inappropriate when the primary purpose is to explain unexpected quantitative results. In that case, quantitative-first explanatory sequential research may provide a better fit.

If quantitative and qualitative components can independently investigate related aspects of a phenomenon during the same period, a convergent arrangement may be appropriate.

Researchers should also consider whether a focused qualitative study or a limited instrument pretesting exercise would adequately address the problem without requiring a full mixed-methods investigation.

Watch Out

Do not use exploratory sequential terminology merely because interviews precede a survey. The qualitative findings must meaningfully shape the quantitative phase, and the resulting measurement or intervention claims must be evaluated using appropriate evidence.

04 · A Practical Example

Developing a Questionnaire About Responsible AI Use in Assessment

Hypothetical Example

From Teachers' Experiences to Quantitative Measurement

A researcher wants to investigate responsible generative AI use in university assessment. Existing questionnaires do not adequately represent the assessment practices and institutional conditions relevant to the intended population.

The researcher therefore proposes an exploratory sequential mixed-methods study.

Phase 1: Qualitative exploration

Conduct purposive interviews with teachers representing different disciplines and assessment responsibilities. Investigate how they understand responsible AI use and what practices they consider relevant.

Qualitative analysis

Identify candidate dimensions and contextual distinctions, comparing the findings with relevant theory and previous research.

Integration through instrument development

Translate relevant findings into candidate questionnaire items, documenting the relationship between qualitative evidence and measurement decisions.

Pretesting and refinement

Evaluate item relevance and comprehensibility through appropriate expert and target-population procedures, including cognitive interviewing where useful.

Phase 2: Quantitative evaluation

Administer the instrument to an appropriately selected sample and investigate its measurement properties and relevant quantitative research questions.

Integrated interpretation

Explain how qualitative findings shaped the questionnaire, which proposed dimensions received empirical support, and which aspects require further refinement.

Suppose the interviews suggest candidate dimensions concerning disclosure of AI assistance, verification of AI-generated materials, and responsibility for assessment decisions.

These dimensions could inform questionnaire development, but they should not automatically be treated as established measurement factors.

The quantitative phase might support the proposed structure, reveal substantial overlap among dimensions, or indicate that some items require revision.

The study is exploratory sequential because qualitative understanding directly informs the subsequent quantitative investigation. The design's contribution lies in this developmental relationship and the evidence obtained through appropriate quantitative evaluation.

05 · What Researchers Often Get Wrong

Common Misconceptions About Exploratory Sequential Mixed Methods

Misconception

Does Conducting Interviews Before a Survey Automatically Establish Exploratory Sequential Research?

No. The qualitative findings must meaningfully inform the quantitative component. Chronological order alone does not establish the developmental integration required by the design.

Misconception

Must Every Qualitative Theme Become a Survey Dimension?

No. Themes may represent contextual conditions, overlapping concepts, or complex processes that do not correspond to distinct measurable constructs. Development requires conceptual and methodological judgment.

Misconception

Does Qualitative-First Sequencing Mean Qualitative Priority?

No. The quantitative phase may carry the principal research emphasis, particularly when qualitative exploration primarily supports instrument development. Priority and sequence are separate decisions.

Misconception

Does Developing Items From Interviews Validate the Questionnaire?

No. Interviews can contribute to construct development and content relevance, but the instrument requires appropriate evidence supporting its intended score interpretations and uses.

Misconception

Can Researchers Ignore Existing Theory Because the Study Is Exploratory?

No. Qualitative findings should be considered alongside relevant theoretical and empirical literature. Exploration does not require treating the phenomenon as though nothing is already known.

Misconception

Does a Qualitative-Informed Intervention Automatically Become Effective?

No. Qualitative inquiry may improve contextual relevance and development decisions, but intervention effectiveness requires appropriate evaluation and supporting evidence.

Misconception

Must Both Phases Use the Same Participants?

No. Different samples may be appropriate when qualitative findings inform an instrument or intervention subsequently evaluated in another population. The sampling relationship should support the intended conclusions.

06 · What This Means for You

How to Design an Exploratory Sequential Study That Builds Meaningfully Between Phases

Begin by identifying what is insufficiently understood and why that uncertainty prevents appropriate quantitative investigation.

Then specify what the qualitative phase must establish and how those findings will inform the subsequent component.

A simple decision framework

If the intended construct is insufficiently defined
Consider qualitative exploration to inform conceptualization and candidate measurement dimensions.
If existing instruments do not adequately fit the target population
Consider qualitative-informed adaptation or development followed by appropriate measurement evaluation.
If an intervention requires contextual development
Use qualitative inquiry alongside theory and existing evidence to inform the intervention, then plan suitable evaluation.
If appropriate constructs and measures already exist
Reconsider whether a preliminary qualitative phase adds sufficient value to justify its demands.
If the primary need is to explain unexpected quantitative findings
Consider explanatory sequential research rather than qualitative-first development.

In the methodology, explain how qualitative participants will be selected, how the findings will be analyzed, what developmental decisions will follow, and how the resulting quantitative procedures will be evaluated.

Allocate sufficient time for the transition between phases. Instrument construction, pretesting, and intervention refinement may require substantial work beyond the initial qualitative analysis.

The final report should demonstrate the relationship between phases and distinguish what the qualitative findings suggested from what the quantitative evidence subsequently supported.

07 · A Quick Checklist

Check Whether Your Exploratory Sequential Design Is Methodologically Defensible

Before implementing an exploratory sequential study, check:
Identify the conceptual or contextual uncertainty that requires qualitative exploration.
Review existing theory, instruments, interventions, and relevant empirical evidence.
Select qualitative sampling and analytical procedures appropriate to the exploratory purpose.
Specify how qualitative findings will inform the subsequent quantitative component.
Document the relationship between qualitative findings and developmental decisions.
Plan appropriate instrument pretesting, measurement evaluation, or intervention assessment.
Justify the quantitative sample and analytical procedures according to their intended purpose.
Allow sufficient time for development and refinement between phases.
Integrate the contributions of both phases without overstating validity or effectiveness claims.
08 · Frequently Asked Questions

Frequently Asked Questions About Exploratory Sequential Mixed Methods

What is the main purpose of exploratory sequential mixed-methods research?

Its main purpose is to use qualitative findings to inform a subsequent quantitative investigation, commonly through construct development, instrument construction, intervention development, or identification of relevant variables.

Does exploratory sequential research always begin with interviews?

No. The qualitative phase may use interviews, focus groups, observations, documents, or other appropriate qualitative evidence. The defining feature is the developmental relationship between qualitative findings and the subsequent quantitative component.

Can exploratory sequential mixed methods be used for questionnaire development?

Yes. Qualitative findings can inform constructs and candidate items, while the quantitative phase evaluates measurement properties or investigates subsequent research questions. Appropriate validity evidence is still necessary.

Can the same participants be used in both phases?

Yes, when appropriate, but it is not required. Instrument development studies often use one qualitative sample and a different quantitative sample. The sampling arrangement should support the intended research purpose.

Does the qualitative phase need more participants than the quantitative phase?

No. Each sample should be justified according to its methodological purpose. Qualitative sample adequacy and quantitative sample requirements follow different inferential considerations.

Can exploratory sequential research be used to develop an educational intervention?

Yes. Qualitative inquiry can investigate participant needs and contextual conditions that inform intervention development. Subsequent quantitative evaluation may examine feasibility, implementation, or outcomes, depending on the design.

What if the quantitative findings do not support the original qualitative themes?

Researchers should investigate whether the difference reflects measurement problems, sample differences, conceptual overlap, or substantive complexity. The findings may justify revising the proposed framework rather than rejecting the qualitative evidence outright.

Is exploratory sequential design appropriate when a validated instrument already exists?

Not necessarily. If the instrument is suitable for the intended construct, population, and use, additional qualitative development may be unnecessary. Researchers should justify what the exploratory phase would contribute beyond existing evidence.

09 · The Bottom Line

Use Exploratory Sequential Research When Qualitative Understanding Must Shape Quantitative Inquiry

The Bottom Line

An exploratory sequential mixed-methods design begins with qualitative inquiry, uses its findings to inform the development of a subsequent quantitative component, and integrates both phases to address an overarching research problem.

The design is most defensible when qualitative exploration resolves a genuine developmental need. Researchers should document how the findings shape quantitative procedures, evaluate resulting measures or interventions appropriately, and avoid assuming that sequence alone establishes meaningful integration.

10 · Sources and Further Reading

Authoritative Sources on Exploratory Sequential Mixed Methods

11 · Cite this Guide

How to Cite This Guide

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